VarFish: comprehensive DNA variant analysis for diagnostics and research

VEP-like tool for sequence ontology and HGVS annotation of VCF files

A port of biocommons/hgvs to the Rust programming language

Genome annotation based on Rust and RocksDB

(Legacy) Annotate variants for import into VarFish server.

Setup VarFish as using Docker Compose

A port of biocommons/seqrepo to the Rust programming language

Download public databases for VarFish

VarFish REST API client (CLI + Python package)

Rust-based background worker for varfish-server

VarFish (Snakemake) Client Workflow for Querying Snakemake

DEPRECATED, use https://github.com/bihealth/varfish-docker-compose instead

DEPRECATED Convert annotation database files to Var:fish: import format

Utilities for using RocksDB as read-only lookup table (after initial bulk import)

VarFish (Snakemake) Client Workflow for Validation

(Partial) port of biocommons/bioutils to Rust

Repository for building IGSR data sets for use in VarFish

(Next-generation; in-development) VarFish Docker Compose

Scripts for generating the data used in the VarFish course

Automated evaluation of ACMG rules